New York; Paterson, N. J.
From the College of Physicians and Surgeons, Columbia University (Drs. Brown and Chan) and the North Jersey Training School, Totowa, N. J. (Dr. Yolken).
Recently Avery1 reported a 97% cure rate in a group of 100 patients with enterobiasis (pinworm) who were given a single massive dose (125 mg.) of promethazine (Phenergan) hydrochloride. It is obvious that a therapeutic agent that is this effective, if it is nontoxic, offers great promise not only of curing individual patients but also of eliminating Enterobius infection from families, schools, and institutions for children. A previous study by Sadun and others,2 who treated nine patients with this drug, reported a cure rate of only 44%. In view of Avery's remarkable results and the discrepancy in the results of the two studies, we, in order to verify the results, treated a group of children with promethazine under carefully controlled institutional conditions. A group of children were also treated with pyrathiazine (Pyrrolazote) hydrochloride, a compound closely related to promethazine. To confirm our results, we treated a number of
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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