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RIBOFLAVIN: Title and subTitle BreakDIETARY SOURCES AND REQUIREMENTS

HENRY C. SHERMAN, Ph.D., D.Sc.; CAROLINE SHERMAN LANFORD, Ph.D.
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NEW YORK

From the Department of Chemistry, Columbia University.


JAMA. 1938;110(16):1278-1280. doi:10.1001/jama.1938.62790160013009a
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At the time of the preceding symposium in 1932, the terms vitamin B2 and G were used synonymously by Sure1 as standing for the more heat stable part of the vitamin B complex; and Underhill2 wrote of vitamin G deficiency as "intimately associated with the complex syndrome of symptoms included under the term pellagra." At the time of the present writing (the summer of 1937) the evidence appears conclusive that there are at least three relatively heat stable substances in the vitamin B complex: (1) riboflavin; (2) vitamin B6; and (3) another substance which perhaps may be considered P-P or the Goldberger pellagra-preventive substance, which may or may not be the same as the substance which prevents blacktongue in dogs. (It is also held by some careful students that

REFERENCES

Sure, Barnett:  The Present Status of Vitamin B2 (G) , J. A. M. A. 99:26 ( (July 2) ) 1932;.
Underhill, F. P.:  Clinical Aspects of Vitamin G Deficiency , J. A. M. A. 99: 120 ( (July 9) ) 1932;.
Chick, Harriet; Copping, Alice M., and Edgar, Constance E.:  The Components of Vitamin B2 , Biochem. J. 29:722 ( (March) ) 1935;.
Booher, Lela E.:  Concentration and Chemical Nature of Vitamin G , J. Biol. Chem. 107:591 ( (Nov.) ) 1934;.
Karrer, P.:  Nutritionally Important Natural Pigments , Helv. Chim. Acta 19:E 33 (special number) 1936;.
Heilbron, I. M.; Parry, E. G., and Phipers, R. F.:  The Algae: III. The Isolation of Lactoflavin , Biochem. J. 29: 1382 ( (June) ) 1935;.
Eusterman, G. B., and Wilbur, D. L., in The Vitamins: A Symposium on the Present Status of the Knowledge of Vitamins , Chicago, American Medical Association, 1932;, p. 25.
Sherman, H. C., and Ellis, Lillian N.:  Necessary versus Optimal Intake of Vitamin G , J. Biol. Chem. 104:91 ( (Jan.) ) 1934;.
Sherman, H. C.: Chemistry of Food and Nutrition , ed. 5, New York, Macmillan Company, 1937;.
Daniel, Esther P., and Munsell, Hazel E.:  Vitamin Values of Foods , Bull. U. S. Dept., Agriculture , to be published.
Levine, Harold, and Remington, R. E.:  The Vitamin G Content of Some Foods , J. Nutrition 13: 525 ( (May) ) 1937;.
Hunt, C. H., and Krauss, W. E.:  The Influence of the Ration of the Cow upon the Vitamin B and Vitamin G Content of Milk , J. Biol. Chem. 92: 631 ( (Aug.) ) 1931;.
Bourquin, Anne, and Sherman, H. C.:  Quantitative Determination of Vitamin G , J. Am. Chem. Soc. 53:3501 ( (Sept.) ) 1931;.
György, Paul:  The Distribution of Lactoflavin (and of Vitamin B6) in Natural Products of Animal Origin , Biochem. J. 29: 760 ( (March) ) 1935;.
Day, P. L.:  Vitamin G in Beef and Veal , J. Home Economics 23: 657, 1931;.
Rose, Mary S., and Phipard, Esther H. F.:  Vitamin B and G Values of Peas and Lima Beans Under Various Conditions , J. Nutrition 14: 55 ( (July) ) 1937;.
Stiebeling, Hazel K.: Serial No. R 409, Bureau of Labor Statistics, U. S. Dept. Labor, 1936.
György, Paul:  Investigations on the Vitamin B2 Complex: I-III , Biochem. J. 29: 741 ( (March) ) 1935;.
Halliday, Nellie, and Evans, H. M.:  Dietary Production of the Syndrome of Deficiency of Vitamin B6 , J. Nutrition 13:657 ( (June) ) 1937;.
Page, J. W.:  An Improvement in Experimental Method for Investigation of Vitamin G , Proc. Soc. Exper. Biol. & Med. 30:87 ( (Oct.) ) 1932;.
Rose, Mary S.: Laboratory Handbook for Dietetics , ed. 4, New York, Macmillan Company, 1937;.
Stiebeling, Hazel K.: Publications of the U. S. Dept. Agriculture, 1936, and personal communication to the authors in April 1937.

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Sure, Barnett:  The Present Status of Vitamin B2 (G) , J. A. M. A. 99:26 ( (July 2) ) 1932;.
Underhill, F. P.:  Clinical Aspects of Vitamin G Deficiency , J. A. M. A. 99: 120 ( (July 9) ) 1932;.
Chick, Harriet; Copping, Alice M., and Edgar, Constance E.:  The Components of Vitamin B2 , Biochem. J. 29:722 ( (March) ) 1935;.
Booher, Lela E.:  Concentration and Chemical Nature of Vitamin G , J. Biol. Chem. 107:591 ( (Nov.) ) 1934;.
Karrer, P.:  Nutritionally Important Natural Pigments , Helv. Chim. Acta 19:E 33 (special number) 1936;.
Heilbron, I. M.; Parry, E. G., and Phipers, R. F.:  The Algae: III. The Isolation of Lactoflavin , Biochem. J. 29: 1382 ( (June) ) 1935;.
Eusterman, G. B., and Wilbur, D. L., in The Vitamins: A Symposium on the Present Status of the Knowledge of Vitamins , Chicago, American Medical Association, 1932;, p. 25.
Sherman, H. C., and Ellis, Lillian N.:  Necessary versus Optimal Intake of Vitamin G , J. Biol. Chem. 104:91 ( (Jan.) ) 1934;.
Sherman, H. C.: Chemistry of Food and Nutrition , ed. 5, New York, Macmillan Company, 1937;.
Daniel, Esther P., and Munsell, Hazel E.:  Vitamin Values of Foods , Bull. U. S. Dept., Agriculture , to be published.
Levine, Harold, and Remington, R. E.:  The Vitamin G Content of Some Foods , J. Nutrition 13: 525 ( (May) ) 1937;.
Hunt, C. H., and Krauss, W. E.:  The Influence of the Ration of the Cow upon the Vitamin B and Vitamin G Content of Milk , J. Biol. Chem. 92: 631 ( (Aug.) ) 1931;.
Bourquin, Anne, and Sherman, H. C.:  Quantitative Determination of Vitamin G , J. Am. Chem. Soc. 53:3501 ( (Sept.) ) 1931;.
György, Paul:  The Distribution of Lactoflavin (and of Vitamin B6) in Natural Products of Animal Origin , Biochem. J. 29: 760 ( (March) ) 1935;.
Day, P. L.:  Vitamin G in Beef and Veal , J. Home Economics 23: 657, 1931;.
Rose, Mary S., and Phipard, Esther H. F.:  Vitamin B and G Values of Peas and Lima Beans Under Various Conditions , J. Nutrition 14: 55 ( (July) ) 1937;.
Stiebeling, Hazel K.: Serial No. R 409, Bureau of Labor Statistics, U. S. Dept. Labor, 1936.
György, Paul:  Investigations on the Vitamin B2 Complex: I-III , Biochem. J. 29: 741 ( (March) ) 1935;.
Halliday, Nellie, and Evans, H. M.:  Dietary Production of the Syndrome of Deficiency of Vitamin B6 , J. Nutrition 13:657 ( (June) ) 1937;.
Page, J. W.:  An Improvement in Experimental Method for Investigation of Vitamin G , Proc. Soc. Exper. Biol. & Med. 30:87 ( (Oct.) ) 1932;.
Rose, Mary S.: Laboratory Handbook for Dietetics , ed. 4, New York, Macmillan Company, 1937;.
Stiebeling, Hazel K.: Publications of the U. S. Dept. Agriculture, 1936, and personal communication to the authors in April 1937.
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