Dr. Perrin H. Long assisted with advice and criticism in carrying out this investigation.
Owing to lack of space, reports of illustrative cases have been omitted.
BALTIMORE
From the Brady Urological Institute and the Johns Hopkins Hospital.
During the past two years, numerous reports have appeared in the European literature regarding the action of para-aminobenzenesulfonamide (sulfanilamide) and its related compounds marketed under the proprietary names of Prontosil,1 Prontylin and many other names, on both experimental and clinical infections with beta-hemolytic streptococci. Mice are protected or their survival periods significantly lengthened against many lethal doses of this organism by the administration of these drugs. The results of their use in clinical infections have been most striking. Colebrook1a has reported a series of thirty-six cases of puerperal infection with hemolytic streptococci, treated with prontosil. From this he concluded that the drug caused a definitely beneficial effect, as evidenced by a prompt improvement in symptoms, a drop in temperature and a reduction in the death rate from between 18 and 28.8 per cent to 8 per cent in his series.
The first American report was recently made by
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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