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AIR-BORNE INFECTION: Title and subTitle BreakSANITARY CONTROL

WILLIAM FIRTH WELLS, B.S.; MILDRED WEEKS WELLS, M.D.
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Second part of a paper read before the Harvard University Tercentenary (1636-1936) Symposium on "The Environment and Its Effect upon Man" at the Harvard School of Public Health, Aug. 24, 1936. The first part was published in The Journal, November 21, p. 1698.


CAMBRIDGE, MASS.


JAMA. 1936;107(22):1805-1809. doi:10.1001/jama.1936.02770480037010
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In view of the proved possibility of infectious matter being carried by air, reasonable efforts to free air supplies from living micro-organisms are justified in the light of general sanitary principles. The great reduction of intestinal disease through water purification since the turn of the century might prompt us to hope that some of the diseases transmitted through discharges from the respiratory tract may be checked by methods of controlling air supplies. A study of the effect of ventilating factors on the dispersion and viability of micro-organisms suspended in air20 has already disclosed the efficacy of certain destructive agencies.

Experiments on the disappearance of B. coli in the recirculated air of an air-conditioned room were conducted as a preliminary to the investigation of textile mill humidification referred to previously.12 B. coli seemed to disappear much more rapidly from air when the spray humidifier was operating than when the

REFERENCES

A grant from the Milton Fund for studies on the defects of ventilating factors on dispersion and viability of micro-organisms suspended in air was made by Harvard University.
Wells, W. F., and Fair, G. M.:  Viability of B. Coli Exposed to Ultraviolet Radiation in Air , Science 82: 280 ( (Sept. 20) ) 1935;.
Wells, W. F.:  Some Basic Physical Factors Governing the Bactericidal Action of Ultraviolet Radiation on Micro-Organisms Suspended in Air . J. Bact. , to be published.
Whisler, Benjamin: Unpublished thesis. Harvard University, 1936.
The formulation for simple physical combinations are summarized: If N0 = number of organisms before and N1 = number of organisms after irradiation by light of lethal intensity I for time t, then loge N0N1 = - Klt; and at μ distance from a source I0, = r3-KI0t; and in a sphere of R radius (source at center), maximum = R2 -3KI0t for infinite mixing of air, and minimum = R2 -1.2KI0t for zero mixing of air; and approaching a source at velocity v from + ∞ to r distance from source, = vr -KI0; and passing the source (from + ∞ to — ∞) on a straight line r distance from source, =vr -tKI0, and for a cylinder of R radius with source in axis (from + ∞ to - ∞). maximum = vR -2 KI0 for infinite turbulence, and minimum = v R —1.24 π KI0 for for stream line flow.
Gates, F. L.:  A Study of the Bactericidal Action of Ultraviolet Light , J. Gen. Physiol. 13: 231 ( (Nov.) ) 1929;.
Kindly lent by the Hanovia Chemical Manufacturing Company.
Hart, D.:  Sterilization of the Air in the Operating Room by Special Bactericidal Radiant Energy , J. Thoracic Surg. 6:45-81 ( (Oct.) ) 1936;.

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A grant from the Milton Fund for studies on the defects of ventilating factors on dispersion and viability of micro-organisms suspended in air was made by Harvard University.
Wells, W. F., and Fair, G. M.:  Viability of B. Coli Exposed to Ultraviolet Radiation in Air , Science 82: 280 ( (Sept. 20) ) 1935;.
Wells, W. F.:  Some Basic Physical Factors Governing the Bactericidal Action of Ultraviolet Radiation on Micro-Organisms Suspended in Air . J. Bact. , to be published.
Whisler, Benjamin: Unpublished thesis. Harvard University, 1936.
The formulation for simple physical combinations are summarized: If N0 = number of organisms before and N1 = number of organisms after irradiation by light of lethal intensity I for time t, then loge N0N1 = - Klt; and at μ distance from a source I0, = r3-KI0t; and in a sphere of R radius (source at center), maximum = R2 -3KI0t for infinite mixing of air, and minimum = R2 -1.2KI0t for zero mixing of air; and approaching a source at velocity v from + ∞ to r distance from source, = vr -KI0; and passing the source (from + ∞ to — ∞) on a straight line r distance from source, =vr -tKI0, and for a cylinder of R radius with source in axis (from + ∞ to - ∞). maximum = vR -2 KI0 for infinite turbulence, and minimum = v R —1.24 π KI0 for for stream line flow.
Gates, F. L.:  A Study of the Bactericidal Action of Ultraviolet Light , J. Gen. Physiol. 13: 231 ( (Nov.) ) 1929;.
Kindly lent by the Hanovia Chemical Manufacturing Company.
Hart, D.:  Sterilization of the Air in the Operating Room by Special Bactericidal Radiant Energy , J. Thoracic Surg. 6:45-81 ( (Oct.) ) 1936;.
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