Author Contributions: Dr Bennett-Guerrero had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Bennett-Guerrero, O’Brien, Ferguson, Gammie, Song.
Acquisition of data: Peterson, Gammie, Song.
Analysis and interpretation of data: Bennett-Guerrero, Zhao, O’Brien, Gammie, Song.
Drafting of the manuscript: Bennett-Guerrero, O’Brien, Gammie, Song.
Critical revision of the manuscript for important intellectual content: Zhao, O’Brien, Ferguson, Peterson, Gammie, Song.
Statistical analysis: Zhao, O’Brien, Song.
Obtained funding: Peterson, Song.
Administrative, technical, or material support: Ferguson, Gammie, Song.
Study supervision: Bennett-Guerrero, O’Brien, Ferguson, Gammie, Song.
Financial Disclosures: Dr Bennett-Guerrero is principal investigator (grant R01 HL101382-01 from the National Institutes of Health) for a multicenter study assessing the impact of blood transfusion on peripheral and cerebral oxygenation and the microcirculation. He is also a named inventor on a patent application related to methods of washing red blood cells. No other authors have any disclosures.
Funding/Support: This study was supported by the Society of Thoracic Surgeons (STS) through the National Adult Cardiac Surgery Database and the Duke Clinical Research Institute (DCRI).
Role of the Sponsors: This study was sponsored by the STS. Specifically, the DCRI has a contract with the STS to be their National Cardiac Data Warehouse and Analysis Center. In this role, the DCRI independently harvests data from each participating STS center, creates a national analysis database, and performs statistical analyses. The proposal for this study was submitted to and approved of by the STS National Database Publications Committee. After approval, the manuscript was reviewed by the coauthors and a final version was approved by the publications committee. The STS was involved in the design and conduct of the study; in the collection, management, analysis, and interpretation of the data; and in the review and approval of the manuscript.
Disclaimer: Dr Peterson, a contributing editor for JAMA, was not involved in the editorial review of or the decision to publish this article.