Author Contributions: Dr Center had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Bliuc, T. V. Nguyen, Eisman, Center.
Acquisition of data: N. D. Nguyen, Milch, Eisman, Center.
Analysis and interpretation of data: Bliuc, Eisman, Center.
Drafting of the manuscript: Bliuc, Milch, Eisman, Center.
Critical revision of the manuscript for important intellectual content: N. D. Nguyen, T. V. Nguyen, Eisman, Center.
Statistical analysis: Bliuc, Center.
Obtained funding: N. D. Nguyen, T. V. Nguyen, Eisman, Center.
Administrative, technical, or material support: Center.
Study supervision: Eisman, Center.
Financial Disclosures: Dr Eisman reported that his research has been supported by, or he has provided consultation to, Amgen, deCode, Eli Lilly, GE Lunar, Merck Sharp & Dohme, Novartis, Organon, Pfizer, Roche-GSK, Sanofi-Aventis, and Servier. Dr Center reported that she has given sponsored talks for Eli Lilly, Merck Sharp & Dohme, and Sanofi-Aventis. No other disclosures were reported.
Funding/Support: This study was supported in part by National Health and Medical Research Council (NHMRC) grant 276413. This study also received support from the MBF Living Well Foundation, the Ernst Heine Foundation; and untied grants from Amgen, Merck Sharp & Dohme, Sanofi-Aventis, Servier, and Novartis.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: Janet Watters, RN; Shaye Field, RN; and Glenys Hubbard, RN, Garvan Institute of Medical Research (Dubbo site), provided expert assistance with patient interviews and data collection. Jim McBride assisted with the data management process. Diane Townsen, BAppSc, Radiology Department, Dubbo Hospital, and Peter Bass, BAppSc, Orana Radiology, provided invaluable help with obtaining all fracture reports. Denia Mang, BSc, Garvan Institute of Medical Research, managed the database. Sisters Watters, Field, and Hubbard and Ms Mang received support from the listed grants. There was no financial compensation paid to Mr McBride, Ms Townsen, Mr Bass, or any of the participants in the study.