Author Contributions: Drs Center and Bliuc had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Center, Bliuc, Nguyen, Eisman.
Acquisition of data: Center, Eisman.
Analysis and interpretation of data: Center, Bliuc.
Drafting of the manuscript: Center, Eisman.
Critical revision of the manuscript for important intellectual content: Center, Bliuc, Nguyen, Eisman.
Statistical analysis: Center, Bliuc.
Obtained funding: Center, Nguyen, Eisman.
Administrative, technical, or material support: Eisman.
Study supervision: Center, Eisman.
Financial Disclosures: Dr Eisman reported that his research has been supported by and/or he has provided consultation to Amgen, deCode, Eli Lilly, GE-Lunar, Merck Sharp and Dohme, Novartis, Organon, Pfizer, Roche-GlaxoSmithKline, Sanofi-Aventis, and Servier. Dr Center reported that she has given sponsored talks for Eli Lilly, Merck Sharp and Dohme, and Sanofi-Aventis. Dr Bliuc and Dr Nguyen reported no conflicts of interest.
Funding/Support: This work was partly funded by National Health & Medical Research Council (NH&MRC) grant 276413 (federal granting body) and with unrestricted educational grants from Merck Sharp and Dohme, Eli Lilly, and GE Lunar Corporation.
Role of the Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.
Acknowledgment: We thank Janet Watters, RN, Shaye Field, RN, and Jodie Rattey, BS, from the Garvan Institute of Medical Research and supported by the NH&MRC grant, for their thoughtful approaches to data collection and patient retention. We thank Diane Townsen, BAppSc, from the Radiology Department of Dubbo Hospital and Peter Bass, BAppSc, from Orana Radiology who provided us with all fracture reports. Finally we thank Ivan Kuo, MBBS, from the Garvan Institute of Medical Research for all his valuable input and untiring help in diagram preparation. There was no financial compensation paid to Ms Townsen, Dr Bass, or Dr Kuo or any of the participants in the study.