Author Contributions: Dr Giovannucci had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Strate, Giovannucci.
Acquisition of data: Strate, Liu, Aldoori, Giovannucci.
Analysis and interpretation of data: Strate, Liu, Syngal, Aldoori, Giovannucci.
Drafting of the manuscript: Strate.
Critical revision of the manuscript for important intellectual content: Strate, Liu, Syngal, Aldoori, Giovannucci.
Statistical analysis: Strate, Liu, Giovannucci.
Obtained funding: Strate, Giovannucci.
Administrative, technical, or material support: Giovannucci.
Study supervision: Syngal, Aldoori, Giovannucci.
Financial Disclosures: None reported.
Funding/Support: This study was funded by grant K08 HS14062 from the Agency for Healthcare Research and Quality (Dr Strate); grants P01 CA055075 (Dr Giovannucci) and K24 CA113433 (Dr Syngal) from the National Cancer Institute; and grant R01 HL035464 from the National Heart, Lung, and Blood Institute (Dr Giovannucci).
Role of the Sponsor: The funding sources for this study had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Disclaimer: The views expressed in this article are those of the authors and do not necessarily represent the official views of the National Cancer Institute, the National Institutes of Health, or the Agency for Healthcare Research and Quality.
Previous Presentation: An abstract based on this manuscript was presented at Digestive Disease Week; May 19-23, 2007; Washington, DC.
Additional Contributions: We thank the investigators, staff, and participants of the Health Professionals Follow-up Study, especially the following for their contributions: Luba Bondarenko, MS; Mira Kaufman, MS; Siobhan Saint-Surin, BA; and Elizabeth Frost-Hawes, BA, Harvard School of Public Health, and Shiyu Wei, Harvard University. The acknowledged staff received compensation for their contributions.