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JAMA Clinical Challenge |

Superficial Corneal Growth

Huan J. Chang, MD, MPH
JAMA. 2011;305(23):2467-2468. doi:10.1001/jama.2011.783.
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During a routine office visit, you notice that your patient, a 70-year-old white man, has a small superficial growth on the surface of his right eye that you do not remember seeing before (Figure 1). When you ask about it, your patient tells you he has had the lump for about a month. He has had no previous ophthalmic or relevant medical history. He also denies any prior surgery, trauma, or infection. Physical examination is remarkable only for a superficial right corneal lesion.

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Figure 1. Slitlamp photograph of a superficial growth of right cornea (figure reprinted from Arch Ophthalmol. 2010;128[7]:9331)
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Figure 2. Histology of lesion (figure reprinted from Arch Ophthalmol. 2010;128[7]:9331)
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Light microscopy of corneal myxoma. A, Hematoxylin-eosin; original magnification ×200. B, Periodic acid–Schiff; original magnification ×200. C, Alcian blue; original magnification ×400. D, Vimentin; original magnification ×400.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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