Author Contributions: Drs Modi and Rausch had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Modi, Glauser.
Acquisition of data: Modi.
Analysis and interpretation of data: Modi, Rausch, Glauser.
Drafting of the manuscript: Modi, Rausch, Glauser.
Critical revision of the manuscript for important intellectual content: Modi, Rausch, Glauser.
Statistical analysis: Modi, Rausch, Glauser.
Obtained funding: Modi.
Administrative, technical, or material support: Modi, Glauser.
Study supervision: Modi, Glauser.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Modi reports that she has been a consultant for Novartis Pharmaceuticals Inc, which has an interest in antiepileptic drugs. Dr Glauser reports that he is an advisor to, a speaker for, and has received research grants from companies with interests in antiepileptic drugs, including ucb Pharma, Eisai, Upsher-Smith, Lundbeck, Sunovion, Supernus, and Questcor. No other disclosures were reported.
Funding/Support: This research was funded by grant K23HD057333 from the National Institutes of Health awarded to Dr Modi.
Role of the Sponsor: The study sponsors had no role in the design and conduct of the study; in the collection, management, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We thank the research assistants, undergraduate and graduate students, predoctoral interns, and postdoctoral fellows at Cincinnati Children's Hospital Medical Center for recruiting study patients and data collection. We also thank the new-onset seizure team at Cincinnati Children's Hospital for their support of the study.