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Studies Probe New Anti-HIV Strategy, Long-term Success of Prevention Methods

Joan Stephenson, PhD
JAMA. 2011;305(14):1397-1399. doi:10.1001/jama.2011.433.
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Boston— Giving infusions of CD4 cells that have been genetically edited to bar invasion by HIV might represent a new approach to treating patients with HIV infection, according to preliminary findings of a proof-of-concept study.

Investigators are attempting to genetically modify key immune cells to make them resistant to HIV infection.

In addition to these findings, presented here at the 18th Conference on Retroviruses and Opportunistic Infections, investigators reported new information about the durability of interventions to prevent HIV infection and factors that can limit the effectiveness of such preventive measures.

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Investigators are attempting to genetically modify key immune cells to make them resistant to HIV infection.

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