Author Contributions: Drs Schrijvers and Breteler had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Schrijvers, Breteler.
Acquisition of data: Schrijvers, Koudstaal, Hofman, Breteler.
Analysis and interpretation of data: Schrijvers, Breteler.
Drafting of the manuscript: Schrijvers, Breteler.
Critical revision of the manuscript for important intellectual content: Schrijvers, Koudstaal, Hofman, Breteler.
Statistical analysis: Schrijvers.
Obtained funding: Hofman, Breteler.
Administrative, technical, or material support: Schrijvers, Koudstaal, Hofman, Breteler.
Study supervision: Breteler.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Breteler reported receiving an unrestricted research grant from Pfizer. No other authors reported any disclosures.
Funding/Support: The Rotterdam Study is supported by the Erasmus MC University Medical Center and Erasmus University Rotterdam; the Netherlands Organization for Scientific Research (NWO); the Netherlands Organization for Health Research and Development (ZonMw); the Research Institute for Diseases in the Elderly (RIDE); the Ministry of Education, Culture, and Science; the Ministry of Health, Welfare, and Sports; the European Commission (DG XII); and the Municipality of Rotterdam. This study was financially supported by grant IIRG-06-27261 from the Alzheimer's Association and by an unrestricted research grant from Pfizer (Dr Breteler).
Role of the Sponsor: The funding organizations and sponsors had no role in the design and conduct of the study, in the collection, management, analysis, and interpretation of the data, or in the preparation, review, or approval of the manuscript.