JAMA. 1903;XL(2):102-103. doi:10.1001/jama.1903.02490020034005.
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The nature and fate of the cells in areas of inflammatory proliferation have been the subject of investigation and discussion among pathologic histologists since the very beginning of cellular pathology. To the student this part of the histology of inflammation no doubt is the reason of much perplexity because of the large number of different kinds of cells that he must learn to recognize and trace to their proper source. For a generation or more it has been taught that the polymorphonuclear leucocytes that migrate from the blood vessels in inflammations do not undergo any further development nor take part actively in the formation of new tissue from which they disappear. The mononuclear forms, or lymphocytes, on the other hand, have continued to offer great obstacles to satisfactory and unanimous agreement as to their exact rôle, especially as regards the formation of new tissue, because of the difficulty in distinguishing


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