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JAMA. 1892;XIX(4):115. doi:10.1001/jama.1892.02420040027009.
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An interesting review of the present status of vaccination has appeared in the Medical News, May 14, by the pen of Dr. John V. Shoemaker. No country has, in recent years, given a more scrupulous attention to the production of lymph than Prussia. Dr. Shoemaker has been supplied by the Berlin Institute for Animal Vaccination, which is in the charge of Dr. Pissin, State Councillor of Health. This institute was established in 1865, and Dr. Pissen has been a contributor to the literature of small-pox prevention since 1868. The lymph-products of Dr. Pissen have become so favorably known in the country of their origin, that they are exclusively employed as the material for vaccination and re-vaccination in the German army. The lymph is obtained solely by calf-to-calf vaccination. The animals are subjected to rigid examination, and every discoverable source of impurity and contamination is carefully eliminated.

"This lymph is put


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