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S. R. Karpeles, M.D.
JAMA. 1912;LIX(25):2254-2255. doi:10.1001/jama.1912.04270140058024.
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With the present wide use of tincture of iodin for skin sterilization, the following case and deduction may prove of interest and value:1

Mrs. N. applied for treatment for an infected right indexfinger, Oct. 3, 1912. The skin covering the linger and over the anterior and posterior surfaces of its metacarpal bone was disinfected with tincture of iodin. A three-quarter-inch incision over the distal phalanx evacuated a little pus; a small drain was inserted into the wound and the finger and hand were covered with gauze soaked in 1:1,000 mercuric chlorid solution. A gauze bandage covered the finger, hand and wrist. The patient was directed to pour 1:1,000 mercuric chlorid solution over the entire finger every three hours without disturbing the dressing. Because of the severe burning pain the dressing was renewed the following day. An intense dermatitis with many blisters, some fully an inch in diameter, covered the


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