To bridge the gap between a medical education completed 10 or more years ago and the present "information explosion," is a problem not susceptible to any single, simple solution. One of the better palliative measures, the "arm-chair" postgraduate course, is represented by this book. Its essential theme is the concept of "molecular" disease, which not only has become indispensable for theory, but has also penetrated into the daily practice of medicine. From the vast storehouse of recent biochemical knowledge, the editor and four additional contributors have selected some significant topics on which newer information should be more widely disseminated.
In an illuminating chapter on the biochemical basis of the newer diagnostic methods in clinical medicine O. Bodansky discusses catecholamines in relation to pheochromocytoma; the significance of 5-hydroxytryptamine in malignant carcinoid; problems of bilirubin determination and metabolism; and porphyrias and porphyrin metabolism. In another excellent contribution E. Farber deals with selected