0
ARTICLE |

Psychotogenic Properties of Cyclopentolate

Harry H. Mark, MD
JAMA. 1963;186(4):430-431. doi:10.1001/jama.1963.63710040009018c.
Text Size: A A A
Published online

IT IS ALWAYS unpleasant for the physician and patient to be confronted with peculiar, unexpected reactions to a drug which was administered for its beneficial effects. The drug in this case is cyclopentolate (Cyclogyl) hydrochloride, an anticholinergic agent used in eye drop form. In customary use of aqueous solutions of 0.5% to 2.0%, cycloplegia and mydriasis occur within 30 min of instillation of one drop into the conjunctival cul-de-sac. Since its introduction some 10 years ago, cyclopentolate gained wide popularity, particularly among ophthalmologists. The rapid onset and short duration of its action made the drug almost ideal for ophthalmoscopy and refraction in children. Furthermore, serious side effects had not been encountered until the recent publication of two such cases.1,2

It is the purpose of this report to illustrate, by way of four cases, the psychotogenic properties of cyclopentolate, and to point out the chemical similarity of the drug to

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();