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Mondor's Disease

James E. Anthony Jr., MD; W. Frank Matthews, MD
JAMA. 1963;185(12):972. doi:10.1001/jama.1963.03060120082034.
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A SELDOM REPORTED, obscure condition with a vague etiological background is Mondor's disease. This condition has been known since the clinical report by Fagge in 1869.

The disease is characterized by the appearance of subcutaneous cords, usually on the chest wall and in the region of the breast. Usually, though not always, the cords are nontender and may, on tension of the skin, give a bowstring appearance or result in a depression or groove.

Until Mondor's report in 1939, only a scattering of case reports was present in the literature. These reports described the subcutaneous cords without reference to the pathological nature of the disease process. At first, Mondor thought that this was a "sclerosing angeitis" and subsequent pathological descriptions have been no more rewarding. There has been evidence that there may be a thrombophlebitis, periarteritis, or perilymphangitis. Others deny the existence of a thrombotic process.

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