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ARTICLE |

The Cystic Duct Syndrome

H. Jay Cozzolino, MD; Franz Goldstein, MD; Roy R. Greening, MD; C. Wilmer Wirts, MD
JAMA. 1963;185(12):920-924. doi:10.1001/jama.1963.03060120030017.
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We have studied seven patients with noncalculous partial cystic duct obstruction, a syndrome which has not been widely recognized in this country. All seven patients complained of right upper quadrant abdominal pain after meals, but routine oral cholecystography demonstrated normally-filling gallbladders without stones. Using cholecystokinin as a gallbladder stimulant in biliary drainage and cholecystography, we were able to demonstrate impaired gallbladder evacuation due to partial cystic duct obstruction in each instance. Reproduction of the patients' spontaneous pain corroborated the diagnosis. Because of the mechanical nature of the obstruction, cholecystectomy was performed in all patients, followed by lasting symptomatic relief. The term, "cystic duct syndrome" is proposed to designate this condition.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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