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May 18, 1963, Vol 184, No. 7 >
ARTICLE | May 18, 1963

Current Status of Anabolic Steroids

Alice E. Fruehan, MD; Thomas F. Frawley, MD
JAMA. 1963;184(7):527-532. doi:10.1001/jama.1963.03700200049009.
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The clinical usefulness of anabolic agents—testosterone and the newer synthetic steroids—has not been clearly defined. After re-examining their position regarding the status of these drugs, the authors conclude that these agents are useful when specific clinical indications exist. Effective use of these compounds depends upon a knowledge of the anabolic effects desired, of the recommended dosage schedule of the drug selected, and of the side effects and contraindications. In the majority of cases, when a clinically effective anabolic agent is needed, the synthetic steroids available at present do not appear to offer any pronounced advantages over the proper use of testosterone.

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