This volume contains a series of ten lectures given in a seminar at the University of California, Los Angeles, in December, 1959. The material has been expanded and updated and aimed at clinicians, house officers, and medical students who wish to gain further insight into the basic mechanisms of anemia. The subjects covered deal with the morphologic, physiologic, biochemical, and immunologic aspects of normal and abnormal red blood cells. There is an excellent chapter, "Autoimmune Hemolytic Disease," with a discussion of the uses and limitations of the Coombs test. There are well-selected chapters, such as "Iron Metabolism and Iron Deficiency Anemia" and "Anemia and the Spleen," with a discussion of clinical syndromes associated with disturbed splenic function. The authors, each an expert in his field, are permitted to expand fully on a topic of their own special interest and inject their personal evaluation and experience. Based on the most recent