Bleeding from lacerations of the cardia of the stomach as a result of prolonged or forceful vomiting was originally described by Mallory and Weiss in 1929. This sequence of events has occurred most often in alcoholics and elderly individuals with gastritis, but may develop in anyone with vomiting or retching. Such lesions are not common, but are important, in that they can be treated satisfactorily when this syndrome is considered. The diagnosis has only been made by keeping the possibility in mind and by operative exposure of the cardia when the severity of the bleeding necessitates it. Treatment has consisted of suture of the lacerations through a gastrotomy. Three successfully treated cases are presented. As familiarity with the problem becomes greater, this obscure cause of gastrointestinal hemorrhage may be found more frequently.