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Viruses and Leukemias

Robert Gerner, MD; George E. Moore, MD
JAMA. 1966;198(5):564. doi:10.1001/jama.1966.03110180108041.
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To the Editor:—  The staff of the Cell Laboratory at Roswell Park Memorial Institute, Buffalo, NY, has a critical need for blood samples from patients with (1) plasma cell leukemia, ( 2) erythremic myelosis ( Di Guglielmo's syndrome or erythroblastic leukemia), (3) megakaryocytic leukemia, (4) eosinophilic leukemia, (5) basophilic leukemia, or (6) major leukemoid reactions associated with malignancy.The white blood cell count must be greater than 20,000/cu mm for the collection procedures. Heparintreated blood samples are sedimented and the leukocytes put in cell cultures. The staff has successfully cultured cells from more than 35 patients with leukemia and leukemoid reactions. In nine instances virus-containing cells have been found. Samples of 20 to 50 ml of blood are needed in most cases.If acceptable, leukapheresis will be done by a member of the staff in the donor hospital. If you can help, please call collect.


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