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Secondary Syphilis With Unusual Clinical Symptoms

C. Wendell Freeman, MD
JAMA. 1966;198(5):563. doi:10.1001/jama.1966.03110180107036.
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To the Editor:—  A 22-year-old man reported to one of our venereal disease clinics on May 26, 1966, complaining of sores on various portions of his body.The patient gave a history of a penile sore with right inguinal adenitis six months earlier. Although serologic testing was done, the results did not become known, no specific treatment was given, and the lesion healed spontaneously following local applications.The new lesion and right inguinal adenitis returned on May 12, 1966. The new lesion was close to but not at the exact location of the original sore. Three or four days later, May 15 or 16, several additional sores appeared on the foreskin. By this time, a rash had erupted on the scrotum. By May 18 or 20, "sores" had appeared on his umbilicus and inside his nostrils. He had nasal stuffiness but no chills, fever, or malaise.There were multiple, soft,


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