Dialysis an aqueous dialysate bath appears to be a safe and effective means of removing lipid-soluble compounds from the body.
James H. Shinaberger, MD, told the Third International Congress of Nephrology that the value of the technique (suggested by experimental evidence) has been demonstrated in clinical trials in three patients with glutethimide intoxication.
The first patient was a 41-year-old woman who had taken 12.5 gm of the drug 14 hours prior to admission in a comatose condition. During four hours of hemodialysis using a lipid dialysate, the level of the glutethimide in her blood fell from 3.9 mg/100 ml to 1.9 mg/100 ml.
"Post-dialysis blood chemistries