Interference Halts 'Ping Pong' Staph

JAMA. 1966;196(8):33. doi:10.1001/jama.1966.03100210019007.
Text Size: A A A
Published online


Atechnique used to halt nursery epidemics has been extended by its originators to interrupt "ping pong" staphylococcal disease in families.

A preliminary study of "bacterial interference" with 14 families indicates the method—which substitutes an avirulent bacterium for the recurrent strain on the nasal mucosa—can be used with outpatients, according to Marvin Boris, MD.

Families in the recent New York City study all had at least a oneyear history of recurrent infection in two or more members. Lesions involved were primarily dermal, but also included four intra-rectal abscess and single instances of osteomyelitis, peritonitis, and septicemia. The same strain of Staphylococcus was isolated from all family members with the same lesion.

Each participant was first given a 10-20 day course of penicillins systemically and antibacterial agents to carrier sites such as the nose.

After two consecutive cultures proved negative for the recurrent bacteria, the major part of the study began.



Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.