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Human Pathology: An Introduction to Medicine

Robert D. Coye, MD
JAMA. 1966;196(4):375. doi:10.1001/jama.1966.03100170117056.
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Morehead's Human Pathology is a very large and almost unbelievably detailed text of pathological anatomy. The author's approach is that of the classical morphologist with heavy emphasis on the location, size, shape, and cellular composition of lesions. Frequently there is a brief summary of the associated clinical findings, but the pathogenesis of the lesion receives very little attention, for much of our present understanding rests on knowledge obtained from techniques other than those of pathologic anatomy. This is not to say that there are no areas in which pathogenesis is not discussed completely—the sections on genetics and the section on the development of peptic ulceration are very well done, but on the whole, this book describes rather than explains the development of the disease.

The format is straightforward with a series of introductory chapters devoted to the cell and the basic disease process. This makes up approximately 10% of the


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