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Agents Affecting Fertility: A Symposium

Larry McGowan, MD
JAMA. 1966;195(13):1159-1160. doi:10.1001/jama.1966.03100130133051.
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The topics covered by the clinicians, pharmacologists, and biologists included antifertility agents of plant origin, nutritional factors affecting fertility, related immunology, chemical control of male fertility, agents affecting insect fertility, nonsteroidal agents inhibiting pituitary gonadotrophic function, mechanism and clinical application of oral contraceptives, central neural block to ovulation, maternally transmitted embryotrophic agents, inhibition of decidualization, and tranquilizers and nidation.

The symposium presented various stimulating aspects, as, for example, the attempt which should be made to recover knowledge concerning antifertility agents of plant origin from cultures collapsing under the impact of civilization, before the knowledge and empirical work is lost to humanity; immunization for controlling fertility; an agent for the selective suppression of spermatogenesis of immobilization of the spermatozoa; agents having great specificity which act by means of neural mechanisms to regulate the reproductive function of the adenohypophysis; and the intrauterine coil, which prevents nidation by producing a slight but constant


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