0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

STEROID-INDUCED GASTRIC ULCER

JAMA. 1966;195(6):484. doi:10.1001/jama.1966.03100060124037.
Text Size: A A A
Published online

Lack of knowledge about the diseases being treated is a major difficulty in assessing the significance of the "therapeutic complications" attributed to corticosteroids. Prominent among the complications is an apparent increase in peptic ulceration (both duodenal and gastric). An investigation reported in 1960, which covered nearly 3,000 rheumatoid arthritis patients, indicates that the recognized incidence of peptic ulcer in rheumatoid arthritis patients seen prior to the steroid era was 3.3%, whereas the incidence for the general patient population was 1%-3%.1 In rheumatoid arthritis patients seen in 1954 and 1957, but not treated systemically with steroids, the incidence of peptic ulceration was 8.1%. This difference is not easily explained; possibly the incidence of peptic ulcer in rheumatoid patients, or the frequency with which it was recognized, or both, were increasing. The 8.1% incidence of peptic ulcer in the patients not treated systemically with corticosteroids is comparable to an incidence of

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();