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The Management of Cerebrovascular Disease

Fletcher McDowell, MD
JAMA. 1966;195(5):398. doi:10.1001/jama.1966.03100050106044.
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The author, Dr. John Marshall, points out the enormous recent increase in the amount of published information on cerebrovascular disease. He is able, in this small volume, to summarize admirably the important advances in the pathophysiology and management of stroke.

He utilizes the current classification of cerebrovascular accidents, which includes the completed stroke, the evolving stroke, and the transient ischemic attack. The clinical section deals, in detail, with these three varieties and with the physical findings which may be used to distinguish among them. Particular attention is paid to the transient ischemic attack, for this provides warning of cerebrovascular disease before permanent neurological damage has occurred.

The present concepts of the pathophysiology of stroke are well discussed in the section on pathology, written by Drs. T. Crawford and M. R. Crompton. They give an excellent review of the neurovascular pathology of the three major subtypes.

Dr. Marshall, emphasizing that cerebral


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