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Laser Radiation for Metastatic Malignant Melanoma

Paul E. McGuff, MD, PhD; Ralph A. Deterling Jr., MD, PhD; Leonard S. Gottlieb, MD
JAMA. 1966;195(5):393-394. doi:10.1001/jama.1966.03100050101035.
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THIS REPORT is that of a 46-year-old white woman of Irish ancestry, whom I first saw in October 1964, whose left thigh revealed on its anterior and medial surfaces multiple malignant metastatic melanoma. These presented as approximately 200 verrucous, blackish-brown lesions, ranging in size from 2 mm to 2.2 cm. At the lower end of an inguinal scar, there was a firm, discrete, 4.0 × 3.3 × 3.1-cm subcutaneous mass.

The clinical impression was multiple metastatic malignant melanoma, recurrent, with widespread involvement of the left thigh, inguinal area, and with a possible large inguinal melanotic mass.

Report of a Case  In April 1963, the patient had a wide excision elsewhere of a black mole from the left lateral aspect of the lower one third of the leg, with a pathological diagnosis of malignant melanoma. This was radically excised, and a skin graft was applied. A radical left-groin dissection was performed


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