The allergist confronted by a patient with uveitis must be prepared to use many different diagnostic approaches and treatments which will be determined by the characteristics of the patient's disease. Close teamwork between allergist and ophthalmologist is essential. The ophthalmologist defines the morphology and course of the ocular lesion and the possible causes indicated thereby. The allergist determines which of these possible causes is present. Both must supervise treatment: the ophthalmologist concerned with the response of the eye; the allergist, with the response of the body, particularly where therapy with systemic effect must be used, such as vaccines, corticosteroids, and antimicrobial agents.