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An Early Human Seminoma

Raymond G. Bunge, MD; James T. Bradbury, ScD
JAMA. 1965;193(11):960-962. doi:10.1001/jama.1965.03090110098032.
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EARLY SEMINOMA of the human testis is seldom detected in the living patient, although routine section of testes removed for other purposes in the younger age group might well result in their detection. For biopsy material, randomly selected for infertility study, to contain a microscopic malignancy is a very rare phenomenon. Indeed, to encounter the same patient months later, with a grossly palpable testicular cancer whose cytology is identical with that in the biopsy, borders on the mystical. This case report precisely demonstrates this chain of events.

Report of a Case  A 27-year-old white man was first seen in February 1962 for fertility-potential evaluation. He had been married for 20 months and no children had been born. There was nothing in the history to suggest noxious agents, trauma, or delayed descent of the testes which might have contributed to his infertility. Erection, ejaculation, and intercourse were entirely satisfactory.A physical


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