Sir Henry Dale recently celebrated his 90th birthday. We can only conjecture what beneficence maintains Sir Henry past the biblical span, to serve as the best of all inspirations to medical scientists. Honors have come to Sir Henry in generous abundance, but the most meangingful, testifying to his distinguished career as a physiologist, is the respect, admiration, and affection accorded him by physicians and scientists in many countries.
This career, while covering many areas of research, including the chemistry of the nervous system, has been particularly productive in its portion devoted to the study of histamine. Riley, whose elegant experiments identified the mast cells as carriers of histamine, has outlined Sir Henry's contributions to this field, largely by quoting from the latter's writings.1 In 1904 Sir Henry begun his association with the Wellcome Physiological Research Laboratories. He recalls that Mr. Wellcome recommended concentrating his efforts on the obscure pharmacology