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More About Thallium

Mitchell R. Zavon, MD
JAMA. 1965;192(9):786. doi:10.1001/jama.1965.03080220050024.
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To the Editor:—  The letter by Solomon Garb, MD, (JAMA191:346 [Jan 25] 1965) commenting on a report on thallium poisoning by Dr. Kingery (JAMA189:849 [Sept 14] 1964) recommends a trial of diphenylthiocarbazone in severe thallium poisoning in man based on its action in dogs. This material, more commonly known as dithizone, has been tried extensively and does not appear to be of any particular value.Thallotoxicosis was reviewed by Dwayne Reed, MD, et al in The Journal (183:516 [Feb 16] 1963), and an article by Lund who did not recommend its use following his studies in rats because of its known diabetogenic action when injected intravenously was referred to by Reed. However, Chamberlain ( Thallium Poisoning, Pediatrics22:1170, 1958) reported on its use in humans. Despite the apparently favorable impression recorded in the Reed article regarding the Chamberlain experience, careful review of the Chamberlain article


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