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Search for Birth Data on Thalidomide-Sensitive Period

Virginia Apgar, MD, MPH
JAMA. 1965;192(2):173. doi:10.1001/jama.1965.03080150103034.
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To the Editor:—  Dr. Widikund Lenz, Director of the Institut für Humangenetik der Universitat, Universitats-Krankenhaus Eppendorf, 2 Hamburg 20, Martinistrasse 52, Germany, is looking for authenticated records of women who took thalidomide in any form between the 35th and 50th day after the beginning of the last menstrual period, and who gave birth to a normal child. In his experience, every woman who took the drug during this "sensitive" period gave birth to an abnormal baby.In view of the diametrically opposed view of certain physicians employed by pharmaceutical firms (ie, G. Sievers: Klinische-statistische studien zu aktvellen missbildungsproblemen, Eine übersicht, Arzneimittelforschung14:605-655 [June] 1964), Dr. Lenz prefers to consider records from physicians not connected with any drug company.The quotation in my communication, "Drugs in Pregnancy (JAMA190:840-841 [Nov 30] 1964) attributed to Dr. Lenz as a personal communication, was originally from Dr. W. G. McBride, of Sydney,


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