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Pancreatic Inflammatory Disease:A Physiologic Approach

Gordon McHardy, MD
JAMA. 1965;191(12):1035. doi:10.1001/jama.1965.03080120069034.
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This is a timely, well-written easily readable, adequately illustrated coverage of pancreatic inflammatory disease by well-qualified authors. It is a remarkable achievement to have condensed so much knowledge of pancreatitis into 182 pages. The breadth of bibliographic research is indicated in the listing of 930 references, which carry through to publications of 1962.

The book is divided into four sections. The first covers the regulation of pancreatic secretion by hormonal and neurogenic factors. The mechanism and control of the exocrine component, fluid and electrolytes, and enzymes, is a composite physiological study. The pancreatic outflow tract, its anomalies, pressure relationship in the biliary-pancreatic ductal system and the potential to disease states therefrom, are depicted.

The second part describes etiological and pathogenetic factors, including infectious, mechanical, metabolic and nutritional, vascular, toxic, allergic, and traumatic. Pathogenesis and the mechanism of symptom manifestation lead in nicely to the following sections, which consider diagnosis and


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