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Gastric Necrosis Due to Prolonged Local Gastric Hypothermia

Joseph R. Cali, MD; John P. Glaubitz, MD; Ray S. Crampton, MD
JAMA. 1965;191(10):858-859. doi:10.1001/jama.1965.03080100076025.
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SINCE THE original observations made by Wangensteen et al1 in 1958 on the effect of gastric freezing and hypothermia on gastric secretion, considerable clinical experience has been obtained with these two modalities of therapy.

Gastric freezing has been used widely in the treatment of duodenal ulcers, with varying results.2,3 Inflow temperatures have varied from —10 C to —20 C, and freezing has been carried out for 45 minutes to one hour. Numerous complications, such as gastric ulcers and varying degrees of gastric necrosis, have been reported4 and are considered directly attributable to the low temperatures employed.

In contrast, gastric hypothermia has been used in the management of massive upper gastro intestinal hemorrhage with very promising results.5-7 The inflow temperatures used in this latter modality have varied between +2 C to +6 C for periods averaging approximately 48 hours.

Since Jan 1, 1963, a program using gastric


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