Herpes Simplex Cervicitis

Goryun Nigogosyan, MD; John W. Mills, MD
JAMA. 1965;191(6):496. doi:10.1001/jama.1965.03080060070019.
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HERPETIC INFECTIONS of the penis,1,2 vagina, and vulva3 -5 are well known and well documented. Their venereal origin was suspected by Unna in 1883, who emphasized their frequent occurrence among prostitutes.6 However, no modern textbook of gynecology or cervical pathology mentions herpetic cervicitis, and we consider the following report worthwhile.

Report of a Case  The patient, a 20-year-old unmarried white female, was seen on March 18, 1964, complaining of a foul vaginal discharge of about two weeks' duration. Her last menstrual period was on Feb 26. The vulva and vagina were intact but there was a large amount of dark-brown purulent material in the vagina. The cervix appeared dark gray to black, edematous, and friable. Punch biopsies were taken from the outer portion of the cervix, causing considerable bleeding which stopped spontaneously.The microscopical examination revealed small pieces of cervical tissue covered by squamous epithelium and masses


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