We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
JAMA 100 Years Ago |


JAMA. 2011;305(24):2583. doi:10.1001/jama.2011.818.
Text Size: A A A
Published online


That there is a prevailing tendency in medicine of late years to minimize the empirical use of drugs, and to rely more largely on intelligent aid to Nature by physical means, cannot be denied. But even the most ardent “therapeutic nihilist” as a rule acknowledges the value of certain drugs at times, and among these the salicylates as a remedy in acute articular rheumatism have occupied a prominent place. Recently, however, Menzer1 has published an article, based on his experiences as a German army surgeon, which contradicts quite forcibly our prevalent conceptions on this subject. He does not dispute the fact that the judicious administration of salicylates may alleviate the symptoms to a marked degree, and so furnish relief to the sufferer and satisfaction to the physician. But in his experience, patients so treated were much more subject to recurrences, and in particular to deforming arthropathies, than were those handled without the use of salicylates. In all, he summarizes the results of his personal observation on 141 patients, of whom eighty-six were given the drug, and fifty-five treated without. Of the former group, eighteen, or 21 per cent., were incapacitated for further military service, and of the latter, four, or only 7 per cent. On the other hand, severe cardiac complications were about half again as frequent in the absence of salicylate treatment, pleuritis was almost four times as frequent, and the average length of treatment was increased from forty-six to seventy-four days. In addition to his own figures, Menzer cites those of several others, notably of Badt2 (324 cases), which support to some extent his position.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.