JAMA. 1900;XXXIV(11):643-647. doi:10.1001/jama.1900.24610110003001a.
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Telluric conditions were at one time looked on as of considerable etiologic importance in the formation of calculi but, at present, their influence in this direction is considered practically nil.

Hirsch1 says that "climatic influences, geologic formation and character of the drinking water as causal factors in the formation of stone find no support in the facts."

Attention was next directed to the method of living, food, etc., of the individual himself, and as a large majority of the stones are of uric acid composition a uric acid diathesis was invented and a near relationship sought between lithiasis and gout.

Concerning the association of gout and stone, Virchow2 says that the common opinion that uric acid kidney and bladder stones have to do with the occurrence of gout is untenable, and that their coexistence is accidental.

Bouchard3 finds that in 1000 cases of gout, there were but


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