My interest was particularly attracted by experience with the following cases:
Case 1.
—On Oct. 9, 1896, there appeared at my office a young man, 28 years of age, who came to consult me about a peculiar skin eruption which had caused him much annoyance, not because of any irritation at the site of the lesions, but rather because of the consequent disfiguration.He gave the following history: He was an American; had been practicing dentistry for four years; was married and the father of two children; had never suffered from any serious disease, and had never had a skin eruption before; there was no history of gonorrhea or chancre. The present eruption occurred about two weeks previously in the form of small red blotches, erythematous in appearance. It was accompanied with violent headache and a feeling of general debility. Since then small papules appeared on the chest, back, face,