ON LATENT INFECTION AND SUBINFECTION, AND ON THE ETIOLOGY OF HEMOCHROMATOSIS AND PERNICIOUS ANEMIA.

ON THE PRESENCE OF BACTERIA IN NORMAL TISSUES.  Similar considerations and similar criticisms may be brought to bear on the observations which have been made with regard to the existence of bacteria in the normal tissues. Time and again observers, like Hauser, ³⁵ Neisser, ³⁶ and yet others, have found the tissues of healthy animals so frequently sterile that the occasional gaining of cultures from the organs has been by them referred to contamination in the admittedly difficult task of removal of organs or parts of organs from the body into sterile receptacles. Thus, for example, Neisser, out of some thirty-seven rabbits, mice and guinea-pigs, which he fed with various pathogenic and non-pathogenic organisms and in certain of which he further set up grave intestinal irritation by giving at the same time croton-oil or powdered glass, failed to gain cultures from growths in the liver, spleen, kidneys, lungs, etc., in