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September 30, 1899, Vol XXXIII, No. 14 >

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ARTICLE | September 30, 1899

RELATION OF URIC ACID TO MIGRAINE.

JOHN A. LICHTY, M.Ph., M.D.
JAMA. 1899;XXXIII(14):837-839. doi:10.1001/jama.1899.92450660027001h.
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It is not strange that the causal relation of uric acid to migraine has repeatedly suggested itself to the minds of physicians, for the etiology of migraine has always been to the clinician what the origin and significance of uric acid has been to the physiologic chemist—a matter of speculation.

The enthusiasm which has arisen in the past decade or more in the study of the secretions and excretions of the living organism, has again awakened investigations referring to the effect of uric acid on the human body, and its relations to disease. So thorough has been this awakening that the foundation principles of pathology and therapeutics seem to have been threatened. Diseases, the etiology and pathology of which were thought to be beyond question, are now considered with reference to uric acid formation. Remedies which were formerly given because they overcame disease, are now given because they counteract the

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