The fifth edition of this well-known treatise, according to the author's preface, has been so largely rewritten and changed, even from the fourth edition, that it is practically a new work. The anatomy and physiology have been brought up to date, and a new feature, that of normal histology, has been added. The morbid anatomy, gross and microscopic, has correspondingly required revision and illustration, and a new chapter on bacteriology as applied to the nose and throat has been written. These have necessitated complete revision and extension of other subjects, and the general result is an entirely different book in many respects. The illustrations have also been increased to correspond with the other changes.
Dr. Browne's former views as to the antitoxin treatment of diphtheria are well known. His discussion of the subject here is brief, too much so in our opinion, and is in striking contrast with his lengthy