A study of the cases of diphtheria treated at the Zurich Children's Hospital from 1874 to 1898 shows, according to the Swiss correspondent of the Lancet, the influence of the antitoxin in reducing the rate of mortality and corroborates the evidence already supplied by statistics from other sources. There were treated, from 1874 to 1891,690 cases, with a mortality of 43.8 per cent.; from 1891 to 1894, 149 cases, with a mortality of 40.3 per cent.; from Oct. 25, 1894, to May 25, 1898, 385 cases (with antitoxin), with a mortality of 9.8 per cent. In the first period there were 404 cases operated on, with a mortality of 60.4 per cent.; in the second 79 cases, with a mortality of 65.8 per cent., and in the third 118 cases, (86 intubation, 32 tracheotomy), with a mortality of 19.4 per cent. In the cases not operated on—286, 70 and 267