From time to time we read articles in which the assertion is made that the administration of quinin during the existence of hemoglobinuria in malarial infection aggravates the symptom. In fact, it is held by some writers and practitioners that quinin will produce this condition in malarial fever. While this view is sustained by some who practice medicine in malarial districts, it can be positively stated that the vast majority of practitioners in those districts do not hold to any such belief.
As we have increased our knowledge concerning the nature of malarial fever and the plasmodium which produces it, to that extent have these vagaries once propounded and upheld been refuted. At a time when malarial fever was believed to be due to carbonic acid, organic material, effluvia, paludism, and various other theories devoid of proof, and at a time when bacteriology and pathology had not been established upon