TREATMENT OF TETANUS BY MEANS OF INTRACEREBRAL INJECTIONS OF ANTITOXIN.

In an editorial abstract which appeared in the Journal a few weeks ago, reference was made to the interesting study of Roux and Borrel concerning the relation of tetanus toxin to nerve-cells. It will be recalled that when the toxin is injected directly into the brain a peculiar form of tetanus, which Roux and Borrel call cerebral tetanus, results. The symptoms are characterized by psychic excitement, intermittent convulsions, motor disturbances and polyuria, and depend upon the fixation of the ganglion cells. It will also be remembered that Wasserman and Takaki were the first to make experiments that called the attention of investigators to this peculiar affinity of the tetanus toxin for the nerve-cells, inasmuch as they showed that the same intimate union between toxin and nerve-cells occurs when bits of nerve substance and toxin are mixed together outside the body. Roux and Borrel also showed that injection of antitoxin into