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JAMA. 1898;XXXI(14):770-771. doi:10.1001/jama.1898.92450140024001k.
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The results here presented to you are the conclusions drawn from the various cases of tobacco amblyopia treated by me during the past seventeen years. The cases selected are intended not only to call attention to the favorable results following treatment, but to serve especially as illustrations of the faith that is in me. The subject has been so exhaustively handled that it is needless to theorize more; practical experience is after all our final teacher.

I employ the term tobacco amblyopia to express a bilateral, retrobulbar neuritis of the optic nerve with central color scotoma, followed later by an atrophy of the nerve occurring in one addicted to the use of tobacco, and so far as known not using any other toxic agent to excess. The condition may be due to a primary hyperemia of the nerve in this location—the interstitial inflammation, with later the formation of connective tissue


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