JAMA. 1900;XXXVI(13):886-887. doi:10.1001/jama.1900.52470130034002k.
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There is difference of opinion as to the mortality of the chief venereal diseases, syphilis and gonorrhea. The latter was, until quite recently, regarded as purely local, but after the gonococcus was identified and cultivated, it was found that general infections were frequently caused by this organism. Pleurisy, meningitis, myocarditis and peritonitis, and of late a gonococcemia have all been indentified. These considerations force the conclusion that gonorrhea is not the innocent local disease it was formerly thought to be, with complications largely of a mechanical nature, such as stricture, etc. There will probably be a widening conception of the disease-producing power of the gonococcus, since it has been recognized that, in common with other germs, its pathogenic power depends upon a toxin and not upon the germ itself. The observations of Young show that in many cases the gonococcus can be identified by cultivation when it has escaped detection


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